Description
Nifedipine, is a dihydropyridine Ca-channel blocker that prevents Ca ions from entering the slow channels or select voltage-sensitive areas of the vascular smooth muscle and myocardium during depolarisation, producing coronary vascular smooth muscle relaxation and coronary vasodilation. It also reduces peripheral and coronary vascular resistance, resulting in increased coronary blood flow, cardiac output and stroke volume while lowering afterload.
Onset: Immediate-release: Approx 20 minutes.